Selling Home and Going Full-Time

I would like to hear from those of you who made the decision to sell home and personal belongings to hit the road full-time. While it might be nice to retain a home-base keeping a home-base might limit the amount we can travel due to the cost of maintaining a residence. Storing personal belongings just leaves something behind to worry about. Any words of wisdom from those of you who took the leap. Clipper30